Apparent diffusion coefficient in the evaluation of cerebral gliomas malignancy

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Apparent diffusion coefficient in the evaluation of cerebral gliomas malignancy.

BACKGROUND/AIM Magnetic resonance imaging (MRI) is a key modality not only for lesion diagnosis, but also to evaluate the extension, type and grade of the tumor. Advanced MRI techniques provide physiologic information that complements the anatomic information available from conventional MRI. The aim of this study was to determine whether there is a correlation between apparent diffusion coeffic...

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Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas.

BACKGROUND AND PURPOSE Preliminary data indicate that apparent diffusion coefficient (ADC) values may be useful in identifying and grading primary cerebral tumors. We tested the hypothesis that ADC values can be used to differentiate tumor, edema, and normal brain tissue. METHODS Fifteen patients with high-grade cerebral astrocytomas underwent conventional MR imaging, diffusion-weighted MR im...

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The added value of apparent diffusion coefficient to cerebral blood volume in the preoperative grading of diffuse gliomas.

BACKGROUND AND PURPOSE In cerebral gliomas, rCBV correlates with tumor grade and histologic findings of vascular proliferation. Moreover, ADC assesses water diffusivity and is inversely correlated with tumor grade. In the present work, we have studied whether combined rCBV and ADC values improve the diagnostic accuracy of MR imaging in the preoperative grading of gliomas. MATERIALS AND METHOD...

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Grading of Glioma Tumors by Analysis of Minimum Apparent Diffusion Coefficient and Maximum Relative Cerebral Blood Volume

Background: Gliomas are the most common primary neoplasms of the central nervous system. Relative cerebral blood volume (rCBV) could estimate high-grade Gliomas computed with dynamic susceptibility contrast MR imaging which it is artificially lowered by contrast extravasation through a disrupted blood-brain barrier. Objectives: Our intent was to clarify the usefulness of diffusion-weighted m...

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Exploring the Possibility of Estimating Degree of Glioma Tumors by Measuring Apparent Diffusion Coefficient

Introduction: Most common glioma tumors are tumors of the central nervous system (CNS) which are the cause of about 40 to 50 percent of brain tumors. This type of cancer includes 2 to 3 percent of cancers in the world. Conventional MRI is powerless in the detection and differentiation of benign and malignant tumors. In this case, diffusion weighted imaging (DWI) can create cont...

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ژورنال

عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia

سال: 2015

ISSN: 0042-8450,2406-0720

DOI: 10.2298/vsp140229073i